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Distinct elements of the peripheral myelin protein 22 (PMP22) promoter regulate expression in Schwann cells and sensory neurons

✍ Scribed by Marcel Maier; François Castagner; Philipp Berger; Ueli Suter


Book ID
117701559
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
806 KB
Volume
24
Category
Article
ISSN
1044-7431

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Two peripheral myelin protein PMP22 transcripts, CD25 and SR13, have been identified by Northern blot and RNA-polymerase chain reaction (PCR) methods in rat. The 0 2 5 and SR13 mRNA species (each approximately 1.8 kb in size) differ significantly in their 5'-untranslated region (5'-UTR) sequences bu