𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Distinct cytokine patterns differentiate early vs. late colitis in IL-10-deficient mice

✍ Scribed by D.M. Spencer; A.D. Levine

Book ID
119629547
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
173 KB
Volume
32
Category
Article
ISSN
1590-8658

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Gene expression patterns in experimental
Gene expression patterns in experimental colitis in IL-10-deficient mice
✍ Jonathan J. Hansen; Lisa Holt; R. Balfour Sartor πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 753 KB

## Background: While others have described gene expression patterns in humans with inflammatory bowel diseases and animals with chemically induced colitis, a genome-wide comparison of gene expression in genetically susceptible animals that develop spontaneous colitis has not been reported. ## Meth

Tetomilast suppressed production of proi
Tetomilast suppressed production of proinflammatory cytokines from human monocytes and ameliorated chronic colitis in IL-10-deficient mice
✍ Hitoshi Ichikawa; Susumu Okamoto; Nobuhiko Kamada; Hisashi Nagamoto; Mina T. Kit πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 374 KB

## Background: Tetomilast (opc-6535) was originally developed as a compound inhibiting superoxide production in neutrophils. although its mechanism of action is not completely understood, phosphodiesterase type 4 inhibitory function has been postulated. the therapeutic effect of pde4 inhibitors has