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Distinct changes in gene expression induced by A-Myb, B-Myb and c-Myb proteins

✍ Scribed by Rushton, John J; Davis, Lisa M; Lei, Wanli; Mo, Xianming; Leutz, Achim; Ness, Scott A


Book ID
110067254
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
678 KB
Volume
22
Category
Article
ISSN
0950-9232

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Background. The expression of several genes is modulated during neuroblastoma differentiation. The retinoblastoma family proteins, pRb, p107 and pRb2/p130, act in the repression of proliferation genes, interacting mainly with the E2F transcription factors. Procedure and Results. In this study, we fo