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Distinct and common developmental expression patterns of the murine Pkd2 and Pkd1 genes

✍ Scribed by Richard Guillaume; Marie Trudel


Book ID
118601893
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
593 KB
Volume
93
Category
Article
ISSN
0925-4773

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Murine Pkd1 is a developmentally regulat
✍ Richard Guillaume; Vivette D'Agati; Martin Daoust; Marie Trudel πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 286 KB

PKD1 is the most common genetically mutated gene involved in autosomal dominant polycystic kidney disease (ADPKD). Our previous studies have shown that the pathogenesis of human and murine polycystic kidney disease (PKD) involves failure to switch out of a renal developmental program, suggesting a r