𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Distance dependency of exciton coupled circular dichroism using turn and helical peptide spacers

✍ Scribed by Simona Oancea; Fernando Formaggio; Sandro Campestrini; Quirinus B. Broxterman; Bernard Kaptein; Claudio Toniolo

Publisher
Wiley (John Wiley & Sons)
Year
2003
Tongue
English
Weight
216 KB
Volume
72
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Porphyrins are promising chromophores for the investigation of the still unexplored area of 3‐dimensional structural studies of proteins by using the exciton coupled circular dichroism (CD) method. The synthesis, conformational characterization by FTIR absorption and ^1^H‐NMR, and CD properties are described for a model bis‐porphyrin system based on homooligo‐[L‐(αMe)Val]~n~ peptides as rigid spacers. In particular, the coupled CD phenomenon is experimentally detected, the intensity of which is modulated by the interchromophoric distance. These results extend and integrate those already reported with steroid, dimeric steroid, and brevetoxin bridges. © 2003 Wiley Periodicals, Inc. Biopolymers (Biospectroscopy) 72: 105–115, 2003

📜 SIMILAR VOLUMES

Turn and helical peptide spacers: Combin
Turn and helical peptide spacers: Combined distance and angular dependencies in the exciton-coupled circular dichroism of intramolecularly interacting bis-porphyrins
✍ Ivan Guryanov; Alessandro Moretto; Sandro Campestrini; Quirinus B. Broxterman; B 📂 Article 📅 2006 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 323 KB

## Abstract In a previous study we examined by the exciton‐coupled circular dichroic method the distance effect generated by three‐rigid‐turn and helical‐peptide spacers. In this connection porphyrins were confirmed to be excellent reporter chromophores. In the present investigation we have complet

Helical Chiral Polyisocyanides Possessin
Helical Chiral Polyisocyanides Possessing Porphyrin Pendants: Determination of Helicity by Exciton-Coupled Circular Dichroism
✍ Fumie Takei; Hiroko Hayashi; Kiyotaka Onitsuka; Nagao Kobayashi; Shigetoshi Taka 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 76 KB 👁 1 views

Exciton-coupled circular dichroism of the porphyrin Soret band of triblock copolymers prepared from chiral isocyanide monomers and an achiral tetraphenylporphyrin derivative (TPP) provides a novel method for determining the helical sense of poly(aryl isocyanide)s (see the schematic representation of

Co-oligopeptides of aromatic amino acids
Co-oligopeptides of aromatic amino acids and glycine with a variable distance between the aromatic residues. V. pH-Dependent conformational changes in peptides containing two adjacent tryptophyl residues as evidenced by circular dichroism studies
✍ Vincenzo Rizzo; Pier Luigi Luisi 📂 Article 📅 1977 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 602 KB

## Abstract The influence of pH upon CD spectra of H‐Trp‐Trp‐OH, H‐Trp‐Trp‐Gly‐OH, and H‐Gly‐Trp‐Trp‐OH is investigated and data are compared with those obtained for peptides containing only one tryptophyl residue. A negative Cotton effect at around 225 nm, which in previous work has been related t