Distal deletion of chromosome 1q in an adult
β Scribed by Halal, Fahed ;Vekemans, Michel ;Kaplan, Paige ;Zeesman, Suzan
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 373 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0148-7299
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Hepatocellular carcinoma (HCC) frequently shows a loss of heterozygosity (LOH) on chromosome 4q. In order to define the commonly affected region on chromosome 4q for further positional cloning of the putative tumor suppressor gene, we carried out allelic imbalance (AI) studies in 41 HCCs using a pan
## Abstract We report on a patient with deficiency of distal 6p and compare the clinical and cytogenetic findings in this child with those of three previously reported patients who had similar deletions. Distal del(6p) appears to be associated with a relatively nonβspecific phenotype, with the poss