Dissolution profile for multisized drug particles: New approximate expression

Direct drug loading into preformed porou

Direct drug loading into preformed porous solid dosage units by the controlled particle deposition (CPD), a new concept for improved dissolution using SCF-technology

✍ Ragna S. Wischumerski; Michael Türk; Martin A. Wahl 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

The controlled particle deposition (CPD), a supercritical fluid precipitation process, is used to load porous tablets with ibuprofen to improve drug dissolution. Porous tablets (porosity 44.3 +/- 5.5%), consisting of microcrystalline cellulose pellets and hydroxyethylcellulose, or sugar cubes (poros