Dissociation of the eukaryotic initiation factor-4E/4E-BP1 complex involves phosphorylation of 4E-BP1 by an mTOR-associated kinase
β Scribed by Kate J Heesom; Richard M Denton
- Book ID
- 117111351
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 159 KB
- Volume
- 457
- Category
- Article
- ISSN
- 0014-5793
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Increased phosphorylation of the translational repressor protein 4E-BP1 was found in the cell line derived from the tumor induced in Syrian hamster by Rous sarcoma virus (RSV). This was accompanied by its dissociation from the complex with initiation factor eIF4E. The ribosomal S6 protein kinase p70
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