Dissociation of rod and cone sensitivity by acute localized retinal pigment epithelium loss

Induction of cyclooxygenase-2 gene expre

Induction of cyclooxygenase-2 gene expression in retinal pigment epithelium cells by photoreceptor rod outer segment phagocytosis and growth factors

✍ Alexey V. Ershov; Nicolas G. Bazan 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB

Retinal pigment epithelium (RPE) cells in culture display selective induction of certain early response transcription factors at the onset of photoreceptor rod outer segment (ROS)-specific phagocytosis (Ershov et al., 1996a). Moreover, this response is modulated by prostaglandins. The purpose of thi