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Dissociation of Phosphoinositide Hydrolysis and Cellular Contractility in Hepatic Stellate Cell Activation

✍ Scribed by Yu, Qing ;Yoo, David ;Rockey, Don C.

Book ID
122552072
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
118 KB
Volume
140
Category
Article
ISSN
0016-5085

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## Abstract Hepatic fibrosis is a common response to chronic liver injury and is characterized by increased production of extracellular matrix components, whose major part is produced by hepatic stellate cells activated by inflammatory mediators to proliferate and migrate into the injured regions.