p53 DOES NOT CONTROL THE SPINDLE ASSEMBL
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Anna A Sablina; Larissa S Agapova; Peter M Chumakov; Boris P Kopnin
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Article
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1999
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Elsevier Science
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English
β 318 KB
p53 plays a critical role as a tumour-suppressor in restricting the proliferation of damaged cells, thus preventing formation of genetically altered cell clones. Its inactivation leads, in particular, to accumulation of polyploid and aneuploid cells. To elucidate the role of p53 in control of chromo