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Dissociation of AMP-activated protein kinase and p38 mitogen-activated protein kinase signaling in skeletal muscle

✍ Scribed by Richard C. Ho; Nobuharu Fujii; Lee A. Witters; Michael F. Hirshman; Laurie J. Goodyear

Book ID
116295448
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
184 KB
Volume
362
Category
Article
ISSN
0006-291X

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## Abstract 8‐Cl‐cAMP (8‐chloro‐cyclic AMP), which induces differentiation, growth inhibition and apoptosis in various cancer cells, has been investigated as a putative anti‐cancer drug. Although we reported that 8‐Cl‐cAMP induces growth inhibition via p38 mitogen‐activated protein kinase (MAPK) an