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Dissociation between the translocation and the activation of Akt in fMLP-stimulated human neutrophils--effect of prostaglandin E2

✍ Scribed by Burelout, C.; Naccache, P. H.; Bourgoin, S. G.


Book ID
120391637
Publisher
Society for Leukocyte Biology
Year
2007
Tongue
English
Weight
276 KB
Volume
81
Category
Article
ISSN
0741-5400

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A23 187 stimulates the metabolism of endogenous as well as exogenous arachidonic acid (AA) and eicosapentaenolc acid (EPA) to their corresponding leukotrienes in human neutrophils. In contrast, conflicting results have been obtained concerning the effect of FMLP on the metabolism of these fatty acid