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Dissociated effects of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide–1 on β-cell secretion and insulin clearance in mice

✍ Scribed by Giovanni Pacini; Karl Thomaseth; Bo Ahrén


Book ID
113798985
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
221 KB
Volume
59
Category
Article
ISSN
1532-8600

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## Background: The insulinotropic hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (7-36 amide) (glp-1), regulate insulin secretion to nutrient intake and constitute the endocrine arm of the entero-insular axis. glucagon has been implicated in the pathophysio