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Disseminated Langerhans cell histiocytosis associated with acute myeloid leukaemia: complete remission with daunorubicin and cytarabine

✍ Scribed by Yu-Yan Hwang, Po Tsui, Rock Y. Y. Leung, Yok-Lam Kwong


Book ID
120775646
Publisher
Springer
Year
2012
Tongue
English
Weight
240 KB
Volume
92
Category
Article
ISSN
0939-5555

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We have investigated the effect of cloretazine (VNP40101M or Laromustine), a novel sulfonylhydrazine alkylating agent with significant antileukaemic activity, alone, or combined with cytarabine or daunorubicin, on the proliferation, viability and apoptosis of cell lines and acute myeloid leukaemia b