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Dissection of the C1q–C-reactive protein interaction—A model for understanding the versatile C1q binding to target molecules

✍ Scribed by Lubka T. Roumenina; Krastio Popov; Maria Radanova; Christine Gaboriaud; Veronique Frémeaux-Bacchi; Boris Atanasov

Book ID
116757056
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
81 KB
Volume
45
Category
Article
ISSN
0161-5890

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✍ Holger Neye; Eugen J Verspohl 📂 Article 📅 2004 🏛 BioMed Central 🌐 English ⚖ 648 KB

## Background The pharmacological action of specific immunosuppressants is mediated by immunophilins. While cyclosporin A binds to cyclophilins, FK506/tacrolimus, rapamycin, and others bind to FK506 binding proteins (FKBPs). Different physiological actions of immunophilins were described but their