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Dissecting “Alternative Macrophage Activation”: The role of l-arginine metabolism in chronic inflammation and fibrosis

✍ Scribed by Thomas A. Wynn; Thirumalai Ramalingam; Mark Wilson; Robert Thompson; Margaret Mentink-Kane; Joe Urban; Allen Cheever; Peter Murray; John Pesce


Book ID
116398932
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
109 KB
Volume
48
Category
Article
ISSN
1043-4666

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## Abstract ## Objective Repeated injection of streptococcal cell wall (SCW) fragments results in chronic arthritis in mice. The objective of this study was to identify genes and pathways that determine disease progression based on gene expression profiling in this model. ## Methods Chronic arth