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Disruption of STAT3 signaling leads to tumor cell invasion through alterations of homotypic cell–cell adhesion complexes

✍ Scribed by Rivat, Christine; Wever, Olivier De; Bruyneel, Erik; Mareel, Marc; Gespach, Christian; Attoub, Samir

Book ID
110068514
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
351 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract c‐Met is the receptor for hepatocyte growth factor/scatter factor (HGF/SF). It mediates multiple cellular responses in development and adult life, and c‐Met hyperactivity is associated with malignant transformation of cells and the acquisition of metastatic properties. Signal transducer