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Disruption of six novelSaccharomyces cerevisiae genes reveals thatYGL129c is necessary for growth in non-fermentable carbon sources,YGL128c for growth at low or high temperatures andYGL125w is implicated in the biosynthesis of methionine

✍ Scribed by Tizón, Belén; Rodríguez-Torres, Ana María; Cerdán, María Esperanza

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 315 KB
Volume: 15
Category: Article
ISSN: 0749-503X
DOI: 10.1002/(sici)1097-0061(19990130)15:2<145::aid-yea346>3.0.co;2-j

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✦ Synopsis

Six open reading frames (ORFs) from chromosome VII, YGL131c, YGL129c, YGL128c, YGL125w, YGL124c and YGL121c, were disrupted by deletion cassettes with short flanking regions homologous to the target locus (SFH). YGL129c is necessary for growth in non-fermentable carbon sources, YGL128c for growth at low or high temperatures and YGL125w is implicated in the biosynthesis of methionine. With regard to the other ORFs, basic phenotypic analyses did not reveal any significant clues about their function.