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Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs

✍ Scribed by Colledge, W. H.; Carlton, M. B. L.; Udy, G. B.; Evans, M. J.

Book ID: 109789079
Publisher: Nature Publishing Group
Year: 1994
Tongue: English
Weight: 542 KB
Volume: 370
Category: Article
ISSN: 0028-0836
DOI: 10.1038/370065a0

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Embryonic alkaline phosphatase (EAP) is expressed during the preimplantation period of mouse development; however, its function is unknown. To determine whether the absence of an EAP gene affects development of preimplantation embryos, we studied mice homozygous for the disrupted EAP gene (EAP.ko mi