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Disruption of brain development in male rats exposed prenatally to 5-bromo-2‘-deoxyuridine

✍ Scribed by Makiko Kuwagata; Yoshiaki Saito; Kenji Usumi; Hiroshi Ono; Tetsuji Nagao


Book ID
111300711
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
1021 KB
Volume
41
Category
Article
ISSN
0914-3505

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The effect of 5-fluoro-2´-deoxyuridine (FrdU) on the developing brain and postpubertal reproductive function of male mouse offspring treated prenatally was investigated. FrdU was administered intraperitoneally to pregnant ICR mice at 1.5, 3, 6, 12.5, 25, and 50 mg/kg/day on days 8 through 13 of gest