The insulin receptor has been proposed as a candidate gene for the inherited defect in Type 2 (non-insulin-dependent) diabetes mellitus and we therefore studied three restriction fragment length polymorphic sites, two revealed with the enzyme Sst1 and one by Rsa1, using two insulin receptor cDNA pro
Disproportionate elevation of immunoreactive proinsulin in Type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance
โ Scribed by W. K. Ward; E. C. LaCava; T. L. Paquette; J. C. Beard; B. J. Wallum; D. Porte
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 580 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0012-186X
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๐ SIMILAR VOLUMES
Hepatic glucose production (3H-glucose technique) and insulin-mediated glucose uptake (insulin clamp technique) were measured in 38 Type 2 (non-insulin-dependent) and 11 Type 1 (insulin-dependent) diabetic patients. Fasting plasma glucose concentration was 8.3 4-0.5 mmol/1 in the former, and 9.6 + 1
In non-diabetic subjects, insulin concentrations and insulin resistance are clearly connected, and both correlate with leptin levels, making interpretations about mechanisms difficult. In non-insulin-dependent (Type 2) diabetes mellitus (NIDDM), however, insulin concentrations and insulin resistance
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