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Disposition of Detirelix, A Potent Luteinizing Hormone-Releasing Hormone Antagonist, in Rats and Monkeys

✍ Scribed by Rebecca L. Chan; William Ho; Austin S. Webb; JoAnn LaFargue; Clinton A. Nerenberg

Book ID
114421084
Publisher
Springer US
Year
1988
Tongue
English
Weight
951 KB
Volume
05
Category
Article
ISSN
0724-8741

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The physicochemical properties of A-75998, a synthetic antagonist of luteinizing hormone releasing hormone with potential for treatment of hormone-sensitive cancers and endometriosis, are described. An accelerated solution stability study indicated that the compound is relatively stable and showed a