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Disposition of desloratadine in healthy volunteers

โœ Scribed by Ramanathan, R.; Reyderman, L.; Su, A.-D.; Alvarez, N.; Chowdhury, S. K.; Alton, K. B.; Wirth, M. A.; Clement, R. P.; Statkevich, P.; Patrick, J. E.

Book ID
127331070
Publisher
Informa plc
Year
2007
Tongue
English
Weight
744 KB
Volume
37
Category
Article
ISSN
0049-8254

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Altered flecainide disposition in health
Altered flecainide disposition in healthy volunteers taking quinine
โœ A. Munafo; G. Reymond-Michel; J. Biollaz ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 572 KB

The pharmacokinetics of flecainide and its two sequential metabolites, both free and conjugated, its pharmacodynamics, and the influence of simultaneously administered quinine, have been studied in 10 healthy subjects. The study comprised two, 48-h open phases at an interval of 1 week. Flecainide ac