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Disposition kinetics of taxanes after intraperitoneal administration in rats and influence of surfactant vehicles

✍ Scribed by Koichi Yokogawa; Mingji Jin; Naho Furui; Masaru Yamazaki; Hiromi Yoshihara; Masaaki Nomura; Junko Ishizaki; Ken-ichi Miyamoto; Hiroyuki Furukawa; Sachio Fushida; Kouichi Miwa

Book ID
111769145
Publisher
Pharmaceutical Press
Year
2004
Tongue
English
Weight
281 KB
Volume
56
Category
Article
ISSN
2042-7158

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Disposition kinetics of hepp in rats aft
Disposition kinetics of hepp in rats after intravenous, oral, and intraperitoneal administration. Correlation of plasma and brain levels with the anticonvulsant effects
✍ Lisbeth E. GΓ³mez; Rafael Cueva-RolΓ³n; Pedro A. Lehmann F. πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 610 KB

## Abstract D, L‐3‐hydroxy‐3‐ethyl‐3‐phenylpropanamide (HEPP) is a synthetic drug with anticovulsant effects in a variety of seizure models. HEPP pharmacokinetics was studied after single 50 mg kg^βˆ’1^ intravenous (IV), intraperitoneal (IP), and oral (PO) administration in male albino Wistar rats. T