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Disposition and Metabolism of Metronidazole in Patients with Liver Failure

✍ Scribed by Geoffrey Farrell; Judith Baird-Lambert; Mara Cvejic; Neil Buchanan

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
539 KB
Volume
4
Category
Article
ISSN
0270-9139

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✦ Synopsis

A pharmacokinetic study of metronidazole disposition was performed in 10 patients with severe liver disease, the majority of whom also had impaired renal function. Following a single intravenous dose, systemic clearance of metronidazole was decreased by 66% in patients compared with healthy

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