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Disposition and metabolism of [14-14C] 4-demethoxydaunorubicin HCl (idarubicin) and [14-14C]daunorubicin HCl in the rat

✍ Scribed by Guido Zini; Gian Piero Vicario; Marco Lazzati; Federico Arcamone


Publisher
Springer
Year
1986
Tongue
English
Weight
872 KB
Volume
16
Category
Article
ISSN
0344-5704

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The metabolic fate of 14C-oxaprotiline Β·
✍ Dr. W. Dieterle; J. W. Faigle; W. KΓΌng; W. Theobald πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 426 KB

The disposition of the enantiomers of oxaprotiline has been investigated after single 100 mg oral doses of racemic 14C-labelled oxaprotiline.HC1 in two healthy subjects. Absorption was complete. Peak blood concentrations of total I4C were 804 and 1010ngequiv.g-' after 4-6 h in the two subjects. Afte