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Disposition and biotransformation of 14C-Benzo(a)pyrene in a pig ear skin model: Ex vivo and in vitro approaches

✍ Scribed by Carine Jacques; Elisabeth Perdu; Hélène Duplan; Emilien L. Jamin; Cécile Canlet; Laurent Debrauwer; Jean Pierre Cravedi; Alain Mavon; Daniel Zalko

Book ID: 116923664
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 1005 KB
Volume: 199
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2010.08.001

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## Abstract This study determined and compared the percutaneous penetration and absorption of an organophosphorus (OP) pesticide, parathion (PA), using three experimental skin models: namely the human abdominal‐ and pig‐ear skin __in vitro__ models and the Human Skin grafted onto a nude mouse (HuSk