Nitric oxide (NO) has been proposed to play an important role during neuronal development. Since many of its effects occur during the time of growth cone pathfinding and target interaction, we here test the hypothesis that part of NO's effects might be exerted at the growth cone. We found that low c
โฆ LIBER โฆ
Disoriented pathfinding by pioneer neurone growth cones deprived of filopodia by cytochalasin treatment
โ Scribed by Bentley, David; Toroian-Raymond, Alma
- Book ID
- 109747279
- Publisher
- Nature Publishing Group
- Year
- 1986
- Tongue
- English
- Weight
- 660 KB
- Volume
- 323
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/323712a0
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Nitric oxide has been proposed to play an important role in neuronal development. We have previously shown that growth cones from an identified neuron, B5, in the snail Helisoma trivolvis, respond to nitric oxide (NO) donors by increasing the length of their filopodia within minutes of application (