𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Disorders in blood coagulation in humans occupationally exposed to mercuric vapors

✍ Scribed by Ryszard Wierzbicki; Mirosław Prażanowski; Marta Michalska; Urszula Krajewska; Wojciech P. Mielicki

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
123 KB
Volume
15
Category
Article
ISSN
0896-548X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Changes in blood coagulation system were studied in humans that were occupationally exposed to mercuric vapors. The following parameters were analyzed: mercury concentration in plasma, thrombin generation, thrombin‐antithrombin complexes, soluble fibrin monomers, factor XIII, protein C, platelet factor 4, and β‐thromboglobulin. There was statistically significant increase in the activity of factor XIII, concentration of platelet factor 4 and thrombin generation in plasma of workers exposed to mercuric vapors as compared with unexposed controls. There was also an increase in thrombin‐antithrombin complexes and β‐thromboglobulin concentration accompanied by a decrease in protein C activity in the workers exposed to mercury. However, the last differences were not statistically significant. The data suggest that in humans exposed to mercuric vapors the hemostatic balance is shifted on the hypercoagulative side. J. Trace Elem. Exp. Med. 15:21–29, 2002. © 2002 Wiley‐Liss, Inc.

📜 SIMILAR VOLUMES

Selective determination of elemental mer
Selective determination of elemental mercury in blood and urine exposed to mercury vapor in vitro
✍ Hiroshi Satoh; John B. Hursh; Thomas W. Clarkson; Tsuguyoshi Suzuki 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 518 KB

## Abstract A method is described to ensure quantitative measurement of dissolved mercury vapor (Hg°) in blood and urine. Room air passed through samples of blood and urine carries with it all the dissolved Hg° but leaves behind all the ionic mercury (Hg^++^). Oxidation of Hg° to Hg^++^ in blood sa

Flow cytometric measurement of intracell
Flow cytometric measurement of intracellular bilirubin in human peripheral blood mononuclear cells exposed to unconjugated bilirubin
✍ Yoshio Haga; H. David Kay; Margaret A. Tempero; Rowen K. Zetterman 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 747 KB

Human peripheral blood mononuclear cells were incubated at 37 °C with bilirubin in bovine albumin solution. Histological analysis of bilirubin-treated cells demonstrated a prominent brown pigment deposited in the cytoplasm. Homogenates of these cells in chloroform-methanol solution showed an identic

Elevated sister chromatid exchange frequ
Elevated sister chromatid exchange frequencies in dividing human peripheral blood lymphocytes exposed to 50 Hz magnetic fields
✍ M.A. Wahab; J.V. Podd; B.I. Rapley; R.E. Rowland 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 128 KB 👁 1 views

## Abstract The in vitro cytomolecular technique, sister chromatid exchange (SCE), was applied to test the clastogenic potentiality of extremely low frequency (ELF) electromagnetic fields (EMFs) on human peripheral blood lymphocytes (HPBLs). SCE frequencies were scored in dividing peripheral blood

Genotoxicological investigation of hospi
Genotoxicological investigation of hospital nurses occupationally exposed to ethylene-oxide: I. Chromosome aberrations, sister-chromatid exchanges, cell cycle kinetics, and UV-induced DNA synthesis in peripheral blood lymphocytes
✍ Jenõ Major; Mátyás G. Jakab; Anna Tompa 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 805 KB

Structural, and numeric chromosome aberrations (CA), sisterchromatid exchange (SCE), phytohe magglutinin stimulation (ti), proliferative rate index (PRI), and UV light-induced unscheduled DNA-synthesis (UDS) were investigated in peripheral blood lymphocytes (PBL) of 48 historical controls ("Controls

Hemolysis and deformability of erythrocy
Hemolysis and deformability of erythrocytes exposed to butoxyacetic acid, a metabolite of 2-Butoxyethanol: II. Resistance in red blood cells from humans with potential susceptibility
✍ Mark M. Udden 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB

## Abstract 2‐Butoxyethanol causes hemolysis in rodents but not in humans. 2‐Butoxyethanol‐induced hemolysis is primarily due to the effect of its metabolite 2‐butoxyacetic acid (BAA). 2‐Butoxyacetic acid did not cause hemolytic effects when incubated with blood from a limited number of normal indi