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Disinhibitory effect of phencyclidine in the hippocampus in vitro: PCP receptors implicated

✍ Scribed by Gerald W. Bourne; Barbara Esplin; Radan Čapek


Book ID
115881952
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
561 KB
Volume
150
Category
Article
ISSN
0014-2999

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The phencyclidine (PCP) derivative N-[l-(2-thienyl) cyclohexyl]-piperidine (3H-TCP) was used to label in vivo the N-methyl-D-aspartate (NMDA) receptor-associated ionic channel in the mouse brain. After the injection of a tracer dose of 3H-TCP, a spread labeling throughout the brain was observed, but