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Disentangling cellular proliferation and differentiation in the embryonic stem cell test, and its impact on the experimental protocol

✍ Scribed by Dorien A.M. van Dartel; Nicole J.L. Zeijen; Liset J.J. de la Fonteyne; Frederik J. van Schooten; Aldert H. Piersma


Book ID
113875506
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
880 KB
Volume
28
Category
Article
ISSN
0890-6238

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## Abstract Embryonic stem cells (ESC) have the developmental potential to form every adult cell type, even after prolonged culture. Reproducibly culturing pluripotent populations and directing differentiation has proven technically challenging yet will underpin the provision of stem cells for both