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Diseases associated with the low copy number of the C4B gene encoding C4, the fourth component of complement

โœ Scribed by Szilágyi, Á.; Füst, G.


Book ID
120080449
Publisher
S. Karger AG
Year
2008
Tongue
French
Weight
537 KB
Volume
123
Category
Article
ISSN
1424-8581

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Assessment of complement C4 gene copy nu
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The complement C4 locus is in the class III region of the MHC, and exhibits copy number variation. Complement C4 null alleles have shown association with a number of diseases including systemic lupus erythematosus (SLE). However, most studies to date have used protein immunophenotyping and not direc