His36Pro point-mutated proteolipid prote
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Jonathan Song; Brian D. Goetz; Ian D. Duncan
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Article
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2005
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John Wiley and Sons
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English
β 547 KB
## Abstract The __shaking pup__ (__shp__) is a canine mutation that affects the myelin protein proteolipid protein (PLP) and its smaller and less abundant isoform, DM20, with proline replacing histidine^36^, resulting in a severe myelin deficiency in the central nervous system. We present evidence