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Discussion: Type II and type III collagen in mandibular condylar cartilage of patients with temporomandibular joint pathology

โœ Scribed by J.P Gage


Book ID
113309501
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
104 KB
Volume
53
Category
Article
ISSN
1531-5053

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A heterozygous mutation in the COL2A1 gene was identified in a patient with hypochondrogenesis. The mutation was a single nucleotide transition of G3285T that resulted in an amino acid substitution of Cys for Gly9I3 in the al(I1) chain of type I1 collagen. This amino acid change disrupted the obliga