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DISCUSSION PAPER: THE DETECTION OF MUTAGENIC METABOLITES OF CARCINOGENS IN URINE WITH THE SALMONELLA/MICROSOME TEST

✍ Scribed by Joyce McCann; Bruce N. Ames

Book ID
114882348
Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
261 KB
Volume
269
Category
Article
ISSN
0890-6564

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✍ M. Baumeister; L. LΓΌtzen πŸ“‚ Article πŸ“… 1979 πŸ› Springer-Verlag 🌐 English βš– 343 KB

The carcinogenic nitrofuran, VR-6, was evaluated for mutagenicity in Salmonella typhimurium TA 100 using the plate assay (Ames test). The dose-response curve indicated that S. typhimurium TA 100 is a very sensitive genetic indicator for this chemical class and that basepair substitution appears to b