Discussion: Hereditary Ovarian Cancer
โ Scribed by Beth Y. Karlan; Jeff Boyd; Louise Strong; Judy Garber; Jane Fountain; Uzi Beller
- Book ID
- 112248945
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 26 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0090-8258
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Ovarian cancer is the fourth leading cause of cancer deaths in American women. About 10% of cases are thought to have a hereditary basis, and family history is the strongest known risk factor. In the past, prophylactic oophorectomy has been advocated for women with two or more affected first-degree
There is increasing evidence that hereditary factors play a greater role in ovarian cancer than in any of the other common cancers of adulthood. This is attributable, to a large extent, to a high frequency of mutations in the BRCA1 or BRCA2 genes. In Poland, 3 common founder mutations in BRCA1 accou