Nonopioid-dependent pigeons were trained to discriminate IM injections of 30.0 mg/kg naloxone from water in the procedure in which 15 consecutive responses on one of two keys resulted in grain presentation. Naloxone-appropriate responding was maximal at doses of naloxone equal to and greater than th
Discriminative stimulus properties of haloperidol
โ Scribed by John F. McElroy; Jay J. Stimmel; James M. O'Donnell
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 570 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0272-4391
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After initial exposure to 80 mg/kg, pigeons trained on a two-key drug discrimination procedure rapidly learned to discriminate 120 mg/kg ethosuximide from saline. When 40-160 mg/kg doses of ethosuximide were administered during generalization tests, the percentage of responses directed to the ethosu
Pigeons trained under a two-key drug discrimination procedure eventually learned to discriminate 5 mg/kg phenytoin from saline injections. When 1.25-20 mg/kg doses of phenytoin were substituted for the training dose, the percentage of responses directed to the phenytoin-appropriate key varied direct