Discriminative stimulus properties of ni
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J. A. Pratt; I. P. Stolerman; H. S. Garcha; V. Giardini; C. Feyerabend
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Article
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1983
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Springer
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English
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Rats were trained to discriminate nicotine (0.4 mg/kg SC) from saline in a standard two-bar operant conditioning procedure with food reinforcement. The response to nicotine was dose-related and at the ED50 of 0.14 mg/kg, plasma nicotine concentrations were similar to those reported previously for ci