Discriminative effects of ethylketazocine in the rat: Stereospecificity and antagonism by naloxone
โ Scribed by Seymore Herling; Harlan E. Shannon
- Book ID
- 118940942
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 235 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0024-3205
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The capacity of the specific narcotic antagonists naltrexone and naloxone to block the discriminative effects produced by morphine in the rat were evaluated using a two-choice, discrete-trial avoidance task. The antagonists produced a dose-dependent and time-dependent blockade of morphine's effects
The action of naloxone (0.5 and 2 mg/kg IP) on the behavioural effects of a low (2 g/kg PO) and a high dose (4 g/kg PO) of ethanol was studied in rats. Ethanol at the low dose increased spontaneous motility, enhancing open-field external ambulations and reducing shuttle-box latency. All these effect