Discrimination of transport systems for methylmercury-cysteine uptake in rat erythrocytes by inhibitors and other factors
โ Scribed by Guang Wu
- Book ID
- 119179223
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 847 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1043-6618
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๐ SIMILAR VOLUMES
The present study is a continuation of our experiments on methylmercury-cysteine (MeHg-cysteine) uptake by rat red blood cells (RBCs) at low temperature. Methylmercury-cysteine uptake by rat RBCs was conducted at 5ยฐC and 2OOC. The effects of Ca2+, colchicine, cytochalasin B, 4,4'-diisothiocyano-2,2'
Previous studies have investigated a number of possible transport systems for the uptake of methylmercury (MeHg) in erythrocytes. In the present study, three additional systems were studied. The uptake of MeHg by isolated erythrocytes from rats was studied at 5ุC and 20ุC. Glutamine was used to test
## Abstract Maintenance of appropriate intracellular glutathione (GSH) levels is crucial for cellular defense against oxidative damage. A suggested mechanism of methylmercury (MeHg) neurotoxicity implicates the involvement of oxygen radical formation and a decrease in cellular levels of GSH. Astroc