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Discriminant analysis of DNA polymorphisms in herpes simplex virus type 1 strains involved in primary compared to recurrent infections

โœ Scribed by Kenichi Umene; Chihiro Koga; Tadamitsu Kameyama


Book ID
113767422
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
239 KB
Volume
139
Category
Article
ISSN
0166-0934

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Drug-resistance of herpes simplex virus (HSV) is caused most frequently by mutation of the viral thymidine kinase (TK) gene. To elucidate the significance of detecting nucleotide changes of the TK gene for screening drug-resistant viruses, the frequency and variation of the genetic polymorphisms in