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Discrete lesions of the nigrostriatal dopaminergic system induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the mouse brain

โœ Scribed by Itagaki, Shigeru; Hochi, Toshikazu; Uemura, Shuji; Kimura, Hiroshi


Book ID
122807102
Publisher
Elsevier Science
Year
1986
Weight
73 KB
Volume
3
Category
Article
ISSN
0921-8696

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## Abstract Current behavioral measurements for motor impairment are not consistently sensitive in rodent models of partial nigrostriatal dopamine (DA) depletion. In addition to exploratory and somatosensory behavior, motor skills that are thought to be directly translatable to human Parkinson's di