Discrepancy between portal pressure and systemic hemodynamic changes after incremental doses of propranolol in a wake portal hypertensive rats

The effect of the combination of nitrogl

The effect of the combination of nitroglycerin and propranolol on splanchnic and systemic hemodynamics in a portal hypertensive rat model

✍ Richard J. Kroeger; Roberto J. Groszmann 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 650 KB

Present investigations support major contributions from increases in both portal blood flow and portal vascular resistance in the mechanism that maintains portal hypertension. B-Adrenergic blockers have been shown to reduce the elevated portal blood flow component. The possibility that nitroglycerin