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Discrepancy between Alzheimer-Type Neuropathology and Dementia in Persons with Down's Syndrome

โœ Scribed by HENRYK M. WISNIEWSKI; AUSMA RABE


Book ID
118723990
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
945 KB
Volume
477
Category
Article
ISSN
0890-6564

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Previous research has hypothesized an association between Alzheimer's disease and the amyloid precursor protein W P ) gene found on chromosome 21. We report the case of a 78-year-old woman with Down's syndrome with partial trisomy 21 [46,XX,rec(2l)dup q, inv(21) (p12q22.1)]. No evidence of Alzheimer