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Discovery Process and Pharmacological Characterization of 2-( S )-(4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-( R )-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide (Vestipitant) as a Potent, Selective, and Orally Active NK 1 Receptor Antagonist

✍ Scribed by Di Fabio, Romano; Griffante, Cristiana; Alvaro, Giuseppe; Pentassuglia, Giorgio; Pizzi, Domenica A.; Donati, Daniele; Rossi, Tino; Guercio, Giuseppe; Mattioli, Mario; Cimarosti, Zadeo; Marchioro, Carla; Provera, Stefano; Zonzini, Laura; Montanari, Dino; Melotto, Sergio; Gerrard, Philip A.; Trist, David G.; Ratti, Emiliangelo; Corsi, Mauro

Book ID: 126028271
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 353 KB
Volume: 52
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm900023b

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