Discovery ofα1-antitrypsin deficiency
✍ Scribed by Sten Eriksson
- Book ID
- 110650670
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 464 KB
- Volume
- 168
- Category
- Article
- ISSN
- 0341-2040
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Liver disease related to a-l-antitrypsin deficiency occurs only in Pi ZZ homozygous children. Eleven per cent of Pi ZZ infants present with prolonged neonatal cholestasis. In our group, 25 of 45 Pi ZZ infants with prolonged neonatal cholestasis presented with later cirrhosis. Persistence of jaundice
The human serum protein u,-antitrypsin is the major source of antiprotease activity found in the blood. The protein is synthesised primarily by liver cells but, to a lesser extent, by at least one other cell type. Expression of the gene has provided a paradigm for studies on transcriptional regulati