✦ LIBER ✦

Discovery of TUG-770: A Highly Potent Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonist for Treatment of Type 2 Diabetes

✍ Scribed by Christiansen, Elisabeth; Hansen, Steffen V. F.; Urban, Christian; Hudson, Brian D.; Wargent, Edward T.; Grundmann, Manuel; Jenkins, Laura; Zaibi, Mohamed; Stocker, Claire J.; Ullrich, Susanne; Kostenis, Evi; Kassack, Matthias U.; Milligan, Graeme; Cawthorne, Michael A.; Ulven, Trond

Book ID: 120267996
Publisher: American Chemical Society
Year: 2013
Tongue: English
Weight: 918 KB
Volume: 4
Category: Article
ISSN: 1948-5875
DOI: 10.1021/ml4000673

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of Potent and Selective Agonis

Discovery of Potent and Selective Agonists for the Free Fatty Acid Receptor 1 (FFA 1 /GPR40), a Potential Target for the Treatment of Type II Diabetes

✍ Christiansen, Elisabeth; Urban, Christian; Merten, Nicole; Liebscher, Kathrin; K 📂 Article 📅 2008 🏛 American Chemical Society 🌐 English ⚖ 177 KB

Recent developments in the discovery of

Recent developments in the discovery of FFA1 receptor agonists as novel oral treatment for type 2 diabetes mellitus

✍ Defossa, Elisabeth; Wagner, Michael 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 860 KB

Discovery of Phenylpropanoic Acid Deriva

Discovery of Phenylpropanoic Acid Derivatives Containing Polar Functionalities as Potent and Orally Bioavailable G Protein-Coupled Receptor 40 Agonists for the Treatment of Type 2 Diabetes

✍ Mikami, Satoshi; Kitamura, Shuji; Negoro, Nobuyuki; Sasaki, Shinobu; Suzuki, Mas 📂 Article 📅 2012 🏛 American Chemical Society 🌐 English ⚖ 689 KB

Discovery of ((4 R ,5 S )-5-Amino-4-(2,4

Discovery of ((4 R ,5 S )-5-Amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8 H )-yl)methanone (ABT-341), a Highly Potent, Selective, Orally Efficacious, and Safe Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

✍ Pei, Zhonghua; Li, Xiaofeng; von Geldern, Thomas W.; Madar, David J.; Longenecke 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 190 KB

Correction to Discovery of (2 R )-2-(3-{

Correction to Discovery of (2 R )-2-(3-{3-[(4-Methoxyphenyl)carbonyl]-2-methyl-6-(trifluoromethoxy)-1 H -indol-1-yl}phenoxy)butanoic Acid (MK-0533): A Novel Selective Peroxisome Proliferator-Activated Receptor γ Modulator for the Treatment of Type 2 Diabetes Mellitus with a Reduced Potential to Increase Plasma and Extracellular Fluid Volume

✍ Acton, John J.; Akiyama, Taro E.; Chang, Ching H.; Colwell, Lawrence; Debenham, 📂 Article 📅 2013 🏛 American Chemical Society 🌐 English ⚖ 112 KB