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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives

✍ Scribed by Fabrice Vergne; Patrick Bernardelli; Edwige Lorthiois; Nga Pham; Emmanuelle Proust; Chrystelle Oliveira; Abdel-Kader Mafroud; Pierre Ducrot; Roger Wrigglesworth; Françoise Berlioz-Seux; Francis Coleon; Eric Chevalier; François Moreau; Moulay Idrissi; Anita Tertre; Arnaud Descours; Patrick Berna; Mei Li

Book ID: 108073408
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 308 KB
Volume: 14
Category: Article
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2004.07.009

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