Discovery of the First M 5 -Selective and CNS Penetrant Negative Allosteric Modulator (NAM) of a Muscarinic Acetylcholine Receptor: ( S )-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1 H -imidazo[2,1- a ]isoindol-5(9b H )-one (ML375)

✍ Scribed by Gentry, Patrick R.; Kokubo, Masaya; Bridges, Thomas M.; Kett, Nathan R.; Harp, Joel M.; Cho, Hyekyung P.; Smith, Emery; Chase, Peter; Hodder, Peter S.; Niswender, Colleen M.; Daniels, J. Scott; Conn, P. Jeffrey; Wood, Michael R.; Lindsley, Craig W.

• Book ID: 121361677
• Publisher: American Chemical Society
• Year: 2013
• Tongue: English
• Weight: 716 KB
• Volume: 56
• Category: Article
• ISSN: 0022-2623
• DOI: 10.1021/jm4013246